Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:Mal:activated TLR complex
Synonyms
Definitions

has a Stoichiometric coefficient of 4 Reviewed: Napetschnig, Johanna, 2012-11-16 Edited: Shamovsky, V, 2012-11-06 Reviewed: Gillespie, ME, 2010-11-30 Authored: Shamovsky, V, 2010-06-01 IRAK4 deficient macrophages fail to induce IRAK2 phosphorylation (Kawagoe et al. 2008), suggesting that activated IRAK4 phosphorylates IRAK2 as it does IRAK1.<p>Phosphorylation sites of IRAK2 remain to be characterized.

ID

http://purl.obolibrary.org/obo/HINO_0009120

comment

has a Stoichiometric coefficient of 4

Reviewed: Napetschnig, Johanna, 2012-11-16

Edited: Shamovsky, V, 2012-11-06

Reviewed: Gillespie, ME, 2010-11-30

Authored: Shamovsky, V, 2010-06-01

IRAK4 deficient macrophages fail to induce IRAK2 phosphorylation (Kawagoe et al. 2008), suggesting that activated IRAK4 phosphorylates IRAK2 as it does IRAK1.

Phosphorylation sites of IRAK2 remain to be characterized.

definition source

Pubmed18438411

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/CHEBI_15422

http://purl.obolibrary.org/obo/HINO_0006035

has output

http://purl.obolibrary.org/obo/CHEBI_16761

http://purl.obolibrary.org/obo/HINO_0006037

label

Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:Mal:activated TLR complex

prefixIRI

HINO:0009120

prefLabel

Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:Mal:activated TLR complex

seeAlso

Reactome Database ID Release 43937059

ReactomeREACT_25213

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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