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Dissociation of p-ERK from p-MEK |
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| Definitions |
Reviewed: Gotoh, N, 2011-08-26 p-ERK1/2 dissociates from p-MEK1/2, allowing dimerization of the activated MAPKs and translocation to the nucleus. In FGFR signaling, there is evidence that this dissociation event is negatively regulated by the golgi membrane form of IL17RD, preventing the nuclear localization of activated ERK1/2. Authored: Rothfels, K, 2011-08-15 |
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http://purl.obolibrary.org/obo/HINO_0009060 |
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| comment |
Reviewed: Gotoh, N, 2011-08-26 p-ERK1/2 dissociates from p-MEK1/2, allowing dimerization of the activated MAPKs and translocation to the nucleus. In FGFR signaling, there is evidence that this dissociation event is negatively regulated by the golgi membrane form of IL17RD, preventing the nuclear localization of activated ERK1/2. Authored: Rothfels, K, 2011-08-15 |
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| definition source |
Reactome, http://www.reactome.org Pubmed15239952 Pubmed8388392 |
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| label |
Dissociation of p-ERK from p-MEK |
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| prefixIRI |
HINO:0009060 |
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| prefLabel |
Dissociation of p-ERK from p-MEK |
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| seeAlso |
Reactome Database ID Release 431268206 ReactomeREACT_111113 |
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