loading...| Preferred Name |
p-MEK phosphorylates ERK |
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| Synonyms |
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| Definitions |
has a Stoichiometric coefficient of 2 Reviewed: Gotoh, N, 2011-08-26 MEK1/2 phosphorylate critical tyrosine and threonine residues on ERK1/2, activating the kinase activity of the MAPKs. In FGFR signaling, this reaction appears to be negatively regulated by IL17RD through an unknown mechanism, limiting the extent of MAPK signaling after FGF stimulation. Authored: Rothfels, K, 2011-08-15 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009059 |
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| comment |
has a Stoichiometric coefficient of 2 Reviewed: Gotoh, N, 2011-08-26 MEK1/2 phosphorylate critical tyrosine and threonine residues on ERK1/2, activating the kinase activity of the MAPKs. In FGFR signaling, this reaction appears to be negatively regulated by IL17RD through an unknown mechanism, limiting the extent of MAPK signaling after FGF stimulation. Authored: Rothfels, K, 2011-08-15 |
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| definition source |
Pubmed12807873 Pubmed14742870 Reactome, http://www.reactome.org Pubmed8388392 Pubmed17035228 Pubmed12958313 |
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| label |
p-MEK phosphorylates ERK |
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| prefixIRI |
HINO:0009059 |
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| prefLabel |
p-MEK phosphorylates ERK |
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| seeAlso |
ReactomeREACT_111117 EC Number: 2.7.11 Reactome Database ID Release 431268210 |
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