loading...| Preferred Name |
SPRY2 translocates to the plasma membrane |
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| Definitions |
Reviewed: Gotoh, N, 2011-08-26 SPRY2 translocates to the plasma membrane upon activation of cells with FGF, and translocation is required for the inhibition of growth factor-stimulated cell migration, proliferation and differentiation. Translocation may be mediated by interactions with PIP2 in the membrane, palmitoylation of the C-terminal region of SPRY2 and/or interactions with caveolin-1. Authored: Rothfels, K, 2011-08-15 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009024 |
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| comment |
Reviewed: Gotoh, N, 2011-08-26 SPRY2 translocates to the plasma membrane upon activation of cells with FGF, and translocation is required for the inhibition of growth factor-stimulated cell migration, proliferation and differentiation. Translocation may be mediated by interactions with PIP2 in the membrane, palmitoylation of the C-terminal region of SPRY2 and/or interactions with caveolin-1. Authored: Rothfels, K, 2011-08-15 |
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| definition source |
Reactome, http://www.reactome.org Pubmed11279012 Pubmed12391162 Pubmed10887178 Pubmed11238463 |
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| label |
SPRY2 translocates to the plasma membrane |
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| prefixIRI |
HINO:0009024 |
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| prefLabel |
SPRY2 translocates to the plasma membrane |
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| seeAlso |
ReactomeREACT_111232 Reactome Database ID Release 431295599 |
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