loading...| Preferred Name |
FGFR associated PI3K phosphorylates PIP2 to PIP3 |
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| Definitions |
Reviewed: Gotoh, N, 2011-08-26 Authored: Rothfels, K, 2011-08-15 Once recruited to the activated receptor, PI3K phosphorylates PIP2 to PIP3, leading to activation of AKT signaling. PI3K signaling has been demonstrated in ZMYM2-, FOP- and BCR-FGFR1 fusions (Chen, 2004; Demiroglu, 2001; Guasch, 2001), as well as downstream of a number of other FGFR mutants (see for instance, Byron, 2008; Kunii, 2008; Agazie, 2003; Takeda, 2007). |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009015 |
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| comment |
Reviewed: Gotoh, N, 2011-08-26 Authored: Rothfels, K, 2011-08-15 Once recruited to the activated receptor, PI3K phosphorylates PIP2 to PIP3, leading to activation of AKT signaling. PI3K signaling has been demonstrated in ZMYM2-, FOP- and BCR-FGFR1 fusions (Chen, 2004; Demiroglu, 2001; Guasch, 2001), as well as downstream of a number of other FGFR mutants (see for instance, Byron, 2008; Kunii, 2008; Agazie, 2003; Takeda, 2007). |
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| definition source |
Pubmed11353842 Reactome, http://www.reactome.org Pubmed15863030 |
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| label |
FGFR associated PI3K phosphorylates PIP2 to PIP3 |
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| prefixIRI |
HINO:0009015 |
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| prefLabel |
FGFR associated PI3K phosphorylates PIP2 to PIP3 |
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| seeAlso |
ReactomeREACT_111124 Reactome Database ID Release 431272493 |
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