Preferred Name |
Autophosphorylation of IRE1 dimer |
|
Synonyms |
|
|
Definitions |
has a Stoichiometric coefficient of 2 Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31 Reviewed: Urano, F, 2010-04-30 Dimerization of the N-terminal luminal regions of IRE1-alpha brings the cytosolic C-terminal regions in proximity. The C-terminal region possesses kinase activity and the homodimer trans-autophosphorylates. From homology with Saccharomyces IRE1-alpha the phosphorylation of human IRE1-alpha is believed to be at Ser724. Authored: May, B, 2009-06-02 00:51:49 Edited: May, B, 2009-06-02 00:51:49 |
|
ID |
http://purl.obolibrary.org/obo/HINO_0008878 |
|
comment |
has a Stoichiometric coefficient of 2 Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31 Reviewed: Urano, F, 2010-04-30 Dimerization of the N-terminal luminal regions of IRE1-alpha brings the cytosolic C-terminal regions in proximity. The C-terminal region possesses kinase activity and the homodimer trans-autophosphorylates. From homology with Saccharomyces IRE1-alpha the phosphorylation of human IRE1-alpha is believed to be at Ser724. Authored: May, B, 2009-06-02 00:51:49 Edited: May, B, 2009-06-02 00:51:49 |
|
definition source |
Pubmed9637683 Pubmed16973740 Reactome, http://www.reactome.org Pubmed11069889 |
|
has input | ||
has output | ||
label |
Autophosphorylation of IRE1 dimer |
|
prefixIRI |
HINO:0008878 |
|
prefLabel |
Autophosphorylation of IRE1 dimer |
|
seeAlso |
Reactome Database ID Release 43381091 EC Number: 2.7.11 ReactomeREACT_18399 |
|
subClassOf |