Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Phosphorylation of FRS2-beta by activated FGFR

Synonyms
Definitions

has a Stoichiometric coefficient of 5 Reviewed: Gotoh, N, 2011-08-26 FRS2beta is activated through tyrosine phosphorylation catalyzed by the protein kinase domain of the activated FGFR. By sequence comparison, FRS2beta has the 2 SHP2-binding sites and has three of the four GRB2-binding sites. Authored: de Bono, B, 2007-01-10 10:27:18 Edited: Jupe, S, 2010-02-03 Reviewed: Mohammadi, M, 2007-02-06 21:44:35

ID

http://purl.obolibrary.org/obo/HINO_0008836

comment

has a Stoichiometric coefficient of 5

Reviewed: Gotoh, N, 2011-08-26

FRS2beta is activated through tyrosine phosphorylation catalyzed by the protein kinase domain of the activated FGFR. By sequence comparison, FRS2beta has the 2 SHP2-binding sites and has three of the four GRB2-binding sites.

Authored: de Bono, B, 2007-01-10 10:27:18

Edited: Jupe, S, 2010-02-03

Reviewed: Mohammadi, M, 2007-02-06 21:44:35

definition source

Reactome, http://www.reactome.org

Pubmed12419216

Pubmed9182757

has input

http://purl.obolibrary.org/obo/HINO_0017280

http://purl.obolibrary.org/obo/CHEBI_15422

has output

http://purl.obolibrary.org/obo/CHEBI_16761

http://purl.obolibrary.org/obo/HINO_0017278

label

Phosphorylation of FRS2-beta by activated FGFR

prefixIRI

HINO:0008836

prefLabel

Phosphorylation of FRS2-beta by activated FGFR

seeAlso

ReactomeREACT_111201

Reactome Database ID Release 43191471

EC Number: 2.7.10

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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