Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Autocatalytic phosphorylation of FGFR4

Synonyms
Definitions

The intrinsic protein tyrosine kinase activity of activated FGF receptor 4 catalyzes multiple phosphorylation events, creating a number of binding sites for membrane bound docking proteins to gather intracellular signaling mediators. Based on sequence alignment, FGFR4 contains 5 of the 8 cytoplasmic tyrosine residues identified in FGFR1. has a Stoichiometric coefficient of 10 Authored: de Bono, B, 2007-01-10 10:27:18 Edited: de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22 Reviewed: Mohammadi, M, 2007-02-06 21:44:35

ID

http://purl.obolibrary.org/obo/HINO_0008817

comment

The intrinsic protein tyrosine kinase activity of activated FGF receptor 4 catalyzes multiple phosphorylation events, creating a number of binding sites for membrane bound docking proteins to gather intracellular signaling mediators. Based on sequence alignment, FGFR4 contains 5 of the 8 cytoplasmic tyrosine residues identified in FGFR1.

has a Stoichiometric coefficient of 10

Authored: de Bono, B, 2007-01-10 10:27:18

Edited: de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22

Reviewed: Mohammadi, M, 2007-02-06 21:44:35

definition source

Reactome, http://www.reactome.org

Pubmed8622701

Pubmed1656221

Pubmed11294897

Pubmed1379698

has input

http://purl.obolibrary.org/obo/CHEBI_15422

http://purl.obolibrary.org/obo/HINO_0017272

has output

http://purl.obolibrary.org/obo/CHEBI_16761

http://purl.obolibrary.org/obo/HINO_0011840

label

Autocatalytic phosphorylation of FGFR4

prefixIRI

HINO:0008817

prefLabel

Autocatalytic phosphorylation of FGFR4

seeAlso

Reactome Database ID Release 43190326

EC Number: 2.7.10

ReactomeREACT_9474

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
There are currently no mappings for this class.