Preferred Name |
Autocatalytic phosphorylation of FGFR4 |
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Synonyms |
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Definitions |
The intrinsic protein tyrosine kinase activity of activated FGF receptor 4 catalyzes multiple phosphorylation events, creating a number of binding sites for membrane bound docking proteins to gather intracellular signaling mediators. Based on sequence alignment, FGFR4 contains 5 of the 8 cytoplasmic tyrosine residues identified in FGFR1. has a Stoichiometric coefficient of 10 Authored: de Bono, B, 2007-01-10 10:27:18 Edited: de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22 Reviewed: Mohammadi, M, 2007-02-06 21:44:35 |
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ID |
http://purl.obolibrary.org/obo/HINO_0008817 |
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comment |
The intrinsic protein tyrosine kinase activity of activated FGF receptor 4 catalyzes multiple phosphorylation events, creating a number of binding sites for membrane bound docking proteins to gather intracellular signaling mediators. Based on sequence alignment, FGFR4 contains 5 of the 8 cytoplasmic tyrosine residues identified in FGFR1. has a Stoichiometric coefficient of 10 Authored: de Bono, B, 2007-01-10 10:27:18 Edited: de Bono, B, D'Eustachio, P, 2007-02-10 20:21:22 Reviewed: Mohammadi, M, 2007-02-06 21:44:35 |
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definition source |
Reactome, http://www.reactome.org Pubmed8622701 Pubmed1656221 Pubmed11294897 Pubmed1379698 |
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has input | ||
has output | ||
label |
Autocatalytic phosphorylation of FGFR4 |
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prefixIRI |
HINO:0008817 |
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prefLabel |
Autocatalytic phosphorylation of FGFR4 |
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seeAlso |
Reactome Database ID Release 43190326 EC Number: 2.7.10 ReactomeREACT_9474 |
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subClassOf |