loading...| Preferred Name | Tyrosine kinase inhibitors bind and inhibit FGFR1 fusion dimer phosphorylation | |
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| Definitions |
has a Stoichiometric coefficient of 2 In a murine mouse model of ZNF198-FGFR1-induced EMS, treatment with the FGFR-inhibitor Midostaurin (PKC412) resulted in prolonged survival (Chen, 2004). Similarly, growth of ZNF-198-FGFR1-, FGFR1OP2-FGFR1-, and BCR-FGFR1-expressing lines is blocked by treatment with FGFR-inhibitors (Demiroglu, 2001; Gu, 2006; Chase, 2007; Zhen, 2007; Wasag, 2011). Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15 |
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http://purl.obolibrary.org/obo/HINO_0008627 |
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has a Stoichiometric coefficient of 2 In a murine mouse model of ZNF198-FGFR1-induced EMS, treatment with the FGFR-inhibitor Midostaurin (PKC412) resulted in prolonged survival (Chen, 2004). Similarly, growth of ZNF-198-FGFR1-, FGFR1OP2-FGFR1-, and BCR-FGFR1-expressing lines is blocked by treatment with FGFR-inhibitors (Demiroglu, 2001; Gu, 2006; Chase, 2007; Zhen, 2007; Wasag, 2011). Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15 |
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| definition source |
Pubmed17698633 Pubmed16946300 Pubmed21330321 Pubmed11739186 Reactome, http://www.reactome.org Pubmed15448205 Pubmed17533378 |
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| label |
Tyrosine kinase inhibitors bind and inhibit FGFR1 fusion dimer phosphorylation |
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| prefixIRI |
HINO:0008627 |
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Tyrosine kinase inhibitors bind and inhibit FGFR1 fusion dimer phosphorylation |
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| seeAlso |
ReactomeREACT_120841 Reactome Database ID Release 431839039 |
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