Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

TXNIP is released from oxidized thioredoxin
Synonyms
Definitions

Authored: Jupe, S, 2011-04-28 Edited: Jupe, S, 2011-04-28 ROS induce the dissociation of TXNIP from thioredoxin, freeing TXNIP to subsequently bind NLRP3 and bring about activation of the NLRP3 inflammasome (Zhou et al. 2010). Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06

ID

http://purl.obolibrary.org/obo/HINO_0008527

comment

Authored: Jupe, S, 2011-04-28

Edited: Jupe, S, 2011-04-28

ROS induce the dissociation of TXNIP from thioredoxin, freeing TXNIP to subsequently bind NLRP3 and bring about activation of the NLRP3 inflammasome (Zhou et al. 2010).

Reviewed: Wong, Edmond, 2011-06-06

Reviewed: Kufer, TA, 2011-04-28

Reviewed: Rittinger, K, 2011-06-06

definition source

Pubmed20023662

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/HINO_0003312

has output

http://purl.obolibrary.org/obo/UniProt_Q9H3M7

http://purl.obolibrary.org/obo/UniProt_P10599

label

TXNIP is released from oxidized thioredoxin

prefixIRI

HINO:0008527

prefLabel

TXNIP is released from oxidized thioredoxin

seeAlso

ReactomeREACT_75912

Reactome Database ID Release 431250253

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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