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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Pyrin binds ASC | |
| Synonyms |
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| Definitions |
Authored: Jupe, S, 2010-04-22 has a Stoichiometric coefficient of 3 Edited: Jupe, S, 2011-04-28 Trimeric pyrin interacts with ASC through its Pyrin domains, leading to oligomerization of ASC. This interaction interferes with the ability of NLRP3 (Cyropyrin) to associate with ASC and thus inhibits inflammasome activation (Chae et al. 2003). Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0008478 |
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| comment |
Authored: Jupe, S, 2010-04-22 has a Stoichiometric coefficient of 3 Edited: Jupe, S, 2011-04-28 Trimeric pyrin interacts with ASC through its Pyrin domains, leading to oligomerization of ASC. This interaction interferes with the ability of NLRP3 (Cyropyrin) to associate with ASC and thus inhibits inflammasome activation (Chae et al. 2003). Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06
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| definition source |
Pubmed12667444 Reactome, http://www.reactome.org Pubmed12615073 Pubmed11498534 Pubmed17964261
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| label |
Pyrin binds ASC
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| prefixIRI |
HINO:0008478
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| prefLabel |
Pyrin binds ASC
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| seeAlso |
Reactome Database ID Release 43877361 ReactomeREACT_75855
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