Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

ASC is recruited via a PYD-PYD interaction
Synonyms
Definitions

NLRP3 interacts with ASC (Manji et al. 2003) via their PYD domains (Dowds et al. 2004). NLRP3 oligomerization leads to PYD domain clustering which is believed to facilitate the interaction of NLRP3 with the PYD domain of ASC (Schroder & Tschopp, 2010). Authored: Jupe, S, 2010-04-22 Edited: Jupe, S, 2011-04-28 Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06

ID

http://purl.obolibrary.org/obo/HINO_0008476

comment

NLRP3 interacts with ASC (Manji et al. 2003) via their PYD domains (Dowds et al. 2004). NLRP3 oligomerization leads to PYD domain clustering which is believed to facilitate the interaction of NLRP3 with the PYD domain of ASC (Schroder & Tschopp, 2010).

Authored: Jupe, S, 2010-04-22

Edited: Jupe, S, 2011-04-28

Reviewed: Wong, Edmond, 2011-06-06

Reviewed: Kufer, TA, 2011-04-28

Reviewed: Rittinger, K, 2011-06-06

definition source

Reactome, http://www.reactome.org

Pubmed12615073

Pubmed11786556

Pubmed20303873

has input

http://purl.obolibrary.org/obo/UniProt_Q9ULZ3

http://purl.obolibrary.org/obo/HINO_0012799

has output

http://purl.obolibrary.org/obo/HINO_0003292

label

ASC is recruited via a PYD-PYD interaction

prefixIRI

HINO:0008476

prefLabel

ASC is recruited via a PYD-PYD interaction

seeAlso

Reactome Database ID Release 43844610

ReactomeREACT_75848

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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