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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0008452
http://purl.obolibrary.org/obo/HINO_0008452
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|---|---|
| Preferred Name | MDP elicits a NOD2 response |
| Definitions |
Muramyl dipeptide (MDP) is an essential structural component of bacterial peptidoglycan (PGN) and the minimal elicitor recognized by NOD2. As MDP is present in nearly all bacteria NOD2 is a general sensor of bacteria. NOD2 has additionally been reported to respond to ssRNA (Sabbah et al. 2009) and play a role in T cell activation (Shaw et al. 2011).
Authored: Jupe, S, 2010-04-22
Edited: Jupe, S, 2011-04-28
Reviewed: Wong, Edmond, 2011-06-06
Reviewed: Kufer, TA, 2011-04-28
Reviewed: Rittinger, K, 2011-06-06
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
MDP elicits a NOD2 response
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|---|---|
| comment |
Muramyl dipeptide (MDP) is an essential structural component of bacterial peptidoglycan (PGN) and the minimal elicitor recognized by NOD2. As MDP is present in nearly all bacteria NOD2 is a general sensor of bacteria. NOD2 has additionally been reported to respond to ssRNA (Sabbah et al. 2009) and play a role in T cell activation (Shaw et al. 2011).
Authored: Jupe, S, 2010-04-22
Edited: Jupe, S, 2011-04-28
Reviewed: Wong, Edmond, 2011-06-06
Reviewed: Kufer, TA, 2011-04-28
Reviewed: Rittinger, K, 2011-06-06
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| prefLabel |
MDP elicits a NOD2 response
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| definition source |
Pubmed21251876
Reactome, http://www.reactome.org
Pubmed12527755
Pubmed19701189
Pubmed12514169
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| prefixIRI |
HINO:0008452
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| seeAlso |
ReactomeREACT_75796
Reactome Database ID Release 43168412
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| has input | |
| has output |
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