Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

CYLD deubiquitinates NEMO
Synonyms
Definitions

RIP2-induced ubiquitination of NEMO and consequent NFkappaB activation can be reversed in a dose-responsive manner by the deubiquitinase CYLD, suggesting that CYLD negatively regulates RIP2-induced NEMO ubiquitinylation. Authored: Jupe, S, 2010-04-22 Edited: Jupe, S, 2011-04-28 Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06

ID

http://purl.obolibrary.org/obo/HINO_0008450

comment

RIP2-induced ubiquitination of NEMO and consequent NFkappaB activation can be reversed in a dose-responsive manner by the deubiquitinase CYLD, suggesting that CYLD negatively regulates RIP2-induced NEMO ubiquitinylation.

Authored: Jupe, S, 2010-04-22

Edited: Jupe, S, 2011-04-28

Reviewed: Wong, Edmond, 2011-06-06

Reviewed: Kufer, TA, 2011-04-28

Reviewed: Rittinger, K, 2011-06-06

definition source

Reactome, http://www.reactome.org

Pubmed12917691

Pubmed15620648

has input

http://purl.obolibrary.org/obo/HINO_0006649

has output

http://purl.obolibrary.org/obo/HINO_0005603

http://purl.obolibrary.org/obo/HINO_0006673

label

CYLD deubiquitinates NEMO

prefixIRI

HINO:0008450

prefLabel

CYLD deubiquitinates NEMO

seeAlso

ReactomeREACT_75903

Reactome Database ID Release 43741411

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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