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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | ATP binds to P2X7 | |
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| Definitions |
P2X7 is a receptor for extracellular ATP that acts as a ligand gated non-selective cation channel. It is also responsible for the ATP-dependent lysis of macrophages, which it brings about by mediating the formation of membrane pores permeable to large molecules (Adinolfi et al. 2005). Authored: Jupe, S, 2010-04-22 Edited: Jupe, S, 2011-04-28 Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0008438 |
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| comment |
P2X7 is a receptor for extracellular ATP that acts as a ligand gated non-selective cation channel. It is also responsible for the ATP-dependent lysis of macrophages, which it brings about by mediating the formation of membrane pores permeable to large molecules (Adinolfi et al. 2005). Authored: Jupe, S, 2010-04-22 Edited: Jupe, S, 2011-04-28 Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06
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| definition source |
Pubmed18404507 Reactome, http://www.reactome.org
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| label |
ATP binds to P2X7
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| prefixIRI |
HINO:0008438
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| prefLabel |
ATP binds to P2X7
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| seeAlso |
ReactomeREACT_75791 Reactome Database ID Release 43877178
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