Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

A20 deubiquitinates RIP2
Synonyms
Definitions

Authored: Jupe, S, 2010-04-22 The deubiquitinase A20 is a negative feedback regulator of inflammatory responses, induced by NFkappaB activation (Krikos et al. 1992) and NOD stimulation (Masumoto et al. 2006). A20 can deubiquitinate RIP2 and restricts NOD2 induced signals (Hitosumatsu et al. 2008). Edited: Jupe, S, 2011-04-28 Reviewed: Wong, Edmond, 2011-06-06 Reviewed: Kufer, TA, 2011-04-28 has a Stoichiometric coefficient of 6 Reviewed: Rittinger, K, 2011-06-06

ID

http://purl.obolibrary.org/obo/HINO_0008436

comment

Authored: Jupe, S, 2010-04-22

The deubiquitinase A20 is a negative feedback regulator of inflammatory responses, induced by NFkappaB activation (Krikos et al. 1992) and NOD stimulation (Masumoto et al. 2006). A20 can deubiquitinate RIP2 and restricts NOD2 induced signals (Hitosumatsu et al. 2008).

Edited: Jupe, S, 2011-04-28

Reviewed: Wong, Edmond, 2011-06-06

Reviewed: Kufer, TA, 2011-04-28

has a Stoichiometric coefficient of 6

Reviewed: Rittinger, K, 2011-06-06

definition source

Pubmed18079694

Reactome, http://www.reactome.org

Pubmed16418393

Pubmed18342009

Pubmed1381359

has input

http://purl.obolibrary.org/obo/HINO_0005326

has output

http://purl.obolibrary.org/obo/HINO_0005603

http://purl.obolibrary.org/obo/HINO_0006673

label

A20 deubiquitinates RIP2

prefixIRI

HINO:0008436

prefLabel

A20 deubiquitinates RIP2

seeAlso

ReactomeREACT_75888

Reactome Database ID Release 43688136

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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