Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B
Synonyms
Definitions

Edited: Jupe, S, 2010-09-01 Reviewed: Yan, SD, 2010-11-09 The TRTK-12 fragment of the F-actin capping protein alpha subunit binds S100B in a calcium dependent manner. S100B undergoes a conformational change that is required for subsequent binding to effector proteins (Inman et al. 2002). S100B is a ligand for AGER (Hofmann et al. 1999). In addition this interaction between S100B andF-actin capping protein alpha could be important for regulating actin filament extension (Ivenkov et al. 1995). Authored: Jupe, S, 2010-06-01

ID

http://purl.obolibrary.org/obo/HINO_0008410

comment

Edited: Jupe, S, 2010-09-01

Reviewed: Yan, SD, 2010-11-09

The TRTK-12 fragment of the F-actin capping protein alpha subunit binds S100B in a calcium dependent manner. S100B undergoes a conformational change that is required for subsequent binding to effector proteins (Inman et al. 2002). S100B is a ligand for AGER (Hofmann et al. 1999). In addition this interaction between S100B andF-actin capping protein alpha could be important for regulating actin filament extension (Ivenkov et al. 1995).

Authored: Jupe, S, 2010-06-01

definition source

Pubmed7540176

Reactome, http://www.reactome.org

Pubmed12470955

Pubmed10399917

has input

http://purl.obolibrary.org/obo/HINO_0027180

http://purl.obolibrary.org/obo/HINO_0005960

has output

http://purl.obolibrary.org/obo/HINO_0003521

label

The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B

prefixIRI

HINO:0008410

prefLabel

The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B

seeAlso

ReactomeREACT_25219

Reactome Database ID Release 43879377

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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