Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

PLC-gamma phosphorylation by FGFR mutants

Synonyms
Definitions

has a Stoichiometric coefficient of 4 By analogy with the wild-type pathway, PLC-gamma is presumed to be phosphorylated by activated FGFR mutants, resulting in PLC-gamma activation, stimulation of phosphatidyl inositol hydrolysis and generation of two second messengers, diacylglycerol and inositol (1,4,5) P3. Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15

ID

http://purl.obolibrary.org/obo/HINO_0008191

comment

has a Stoichiometric coefficient of 4

By analogy with the wild-type pathway, PLC-gamma is presumed to be phosphorylated by activated FGFR mutants, resulting in PLC-gamma activation, stimulation of phosphatidyl inositol hydrolysis and generation of two second messengers, diacylglycerol and inositol (1,4,5) P3.

Edited: Rothfels, K, 2012-05-16

Authored: Rothfels, K, 2012-02-09

Reviewed: Ezzat, S, 2012-05-15

definition source

Reactome, http://www.reactome.org

Pubmed10579907

has input

http://purl.obolibrary.org/obo/HINO_0023659

http://purl.obolibrary.org/obo/CHEBI_15422

has output

http://purl.obolibrary.org/obo/HINO_0023656

http://purl.obolibrary.org/obo/CHEBI_16761

label

PLC-gamma phosphorylation by FGFR mutants

prefixIRI

HINO:0008191

prefLabel

PLC-gamma phosphorylation by FGFR mutants

seeAlso

Reactome Database ID Release 432077384

ReactomeREACT_121367

EC Number: 2.7.10

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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