Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Activated PLC-gamma release by activated FGFR mutants

Synonyms
Definitions

Dissociation from the activated receptor quickly follows phosphorylation of PLC-gamma. Phosphorylated PLC-gamma catalyzes the hydrolysis of phosphatidylinositol(4, 5)bisphosphate to generate two second messengers, diacylglycerol and inositol (1,4,5) triphosphate. Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15

ID

http://purl.obolibrary.org/obo/HINO_0008190

comment

Dissociation from the activated receptor quickly follows phosphorylation of PLC-gamma. Phosphorylated PLC-gamma catalyzes the hydrolysis of phosphatidylinositol(4, 5)bisphosphate to generate two second messengers, diacylglycerol and inositol (1,4,5) triphosphate.

Edited: Rothfels, K, 2012-05-16

Authored: Rothfels, K, 2012-02-09

Reviewed: Ezzat, S, 2012-05-15

definition source

Reactome, http://www.reactome.org

Pubmed10579907

has input

http://purl.obolibrary.org/obo/HINO_0023656

has output

http://purl.obolibrary.org/obo/HINO_0004824

http://purl.obolibrary.org/obo/UniProt_P19174

label

Activated PLC-gamma release by activated FGFR mutants

prefixIRI

HINO:0008190

prefLabel

Activated PLC-gamma release by activated FGFR mutants

seeAlso

ReactomeREACT_121068

Reactome Database ID Release 432077385

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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