Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

FGFR4 kinase mutants are inhibited by PD170734

Synonyms
Definitions

has a Stoichiometric coefficient of 2 Treatment of cells expressing FGFR4 N535K or V550E with the in vitro FGFR inhibitor PD170734 reduces the levels of receptor autophosphorylation and increases the activation of caspase-3 and the number of cells undergoing apoptosis (Taylor, 2009). Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15

ID

http://purl.obolibrary.org/obo/HINO_0008174

comment

has a Stoichiometric coefficient of 2

Treatment of cells expressing FGFR4 N535K or V550E with the in vitro FGFR inhibitor PD170734 reduces the levels of receptor autophosphorylation and increases the activation of caspase-3 and the number of cells undergoing apoptosis (Taylor, 2009).

Edited: Rothfels, K, 2012-05-16

Authored: Rothfels, K, 2012-02-09

Reviewed: Ezzat, S, 2012-05-15

definition source

Reactome, http://www.reactome.org

Pubmed19809159

has input

http://purl.obolibrary.org/obo/CHEBI_63448

http://purl.obolibrary.org/obo/HINO_0023635

has output

http://purl.obolibrary.org/obo/HINO_0023644

label

FGFR4 kinase mutants are inhibited by PD170734

prefixIRI

HINO:0008174

prefLabel

FGFR4 kinase mutants are inhibited by PD170734

seeAlso

ReactomeREACT_120902

Reactome Database ID Release 432046363

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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