loading...| Preferred Name |
GRB2-SOS1 is recruited by activated FGFR mutants |
|
| Synonyms |
|
|
| Definitions |
Activation of FGFR mutants has in some cases been shown to result in phosphorylation of both FRS2alpha and ERK1/2, suggesting activation of the MAPK pathway through wild-type like recruitment of the GRB2-SOS1 complex (reviewed in Wesche, 2011; see for instance, Weiss, 2010; Dutt, 2011; Raffioni, 1998; Hart, 2000). Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15 |
|
| ID |
http://purl.obolibrary.org/obo/HINO_0008171 |
|
| comment |
Activation of FGFR mutants has in some cases been shown to result in phosphorylation of both FRS2alpha and ERK1/2, suggesting activation of the MAPK pathway through wild-type like recruitment of the GRB2-SOS1 complex (reviewed in Wesche, 2011; see for instance, Weiss, 2010; Dutt, 2011; Raffioni, 1998; Hart, 2000). Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15 |
|
| definition source |
Reactome, http://www.reactome.org Pubmed10918587 Pubmed21711248 Pubmed21160078 Pubmed9857065 Pubmed21666749 |
|
| has input | ||
| has output | ||
| label |
GRB2-SOS1 is recruited by activated FGFR mutants |
|
| prefixIRI |
HINO:0008171 |
|
| prefLabel |
GRB2-SOS1 is recruited by activated FGFR mutants |
|
| seeAlso |
Reactome Database ID Release 431982082 ReactomeREACT_120735 |
|
| subClassOf |