loading...| Preferred Name |
Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors |
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| Synonyms |
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| Definitions |
has a Stoichiometric coefficient of 2 FGFR2 is inhibited by a range of in vitro tyrosine kinase inhibitors, including PD170734 and SU5402 (reviewed in Greulich and Pollock, 2010; Wesche, 2011). In addition, there are a number of FGFR2 inhibitors currently in clinical trials that for treatment of solid malignancies (http://ClinicalTrials.gov). Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0008094 |
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| comment |
has a Stoichiometric coefficient of 2 FGFR2 is inhibited by a range of in vitro tyrosine kinase inhibitors, including PD170734 and SU5402 (reviewed in Greulich and Pollock, 2010; Wesche, 2011). In addition, there are a number of FGFR2 inhibitors currently in clinical trials that for treatment of solid malignancies (http://ClinicalTrials.gov). Edited: Rothfels, K, 2012-05-16 Authored: Rothfels, K, 2012-02-09 Reviewed: Ezzat, S, 2012-05-15 |
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| definition source |
Reactome, http://www.reactome.org Pubmed21367659 Pubmed21711248 |
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| label |
Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors |
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| prefixIRI |
HINO:0008094 |
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| prefLabel |
Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors |
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| seeAlso |
Reactome Database ID Release 432077424 ReactomeREACT_121289 |
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