Human Interaction Network Ontology

Last uploaded: June 27, 2014
Id http://purl.obolibrary.org/obo/HINO_0008083
http://purl.obolibrary.org/obo/HINO_0008083
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NLRC5 interacts with RIG-I/MDA5 and inhibit IPS-1 binding

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Reviewed: Kawai, T, Akira, S, 2010-10-30 Edited: Garapati, P V, 2010-08-02 NLRC5 competes with IPS-1 for binding to the CARD domain of RIG-I/MDA5. NLRC5 specifically recognize the CARD domains of RIG-I/MDA5 when the CARD domains become accessible after viral infection, leading to dampened activation of IRF3. Authored: Garapati, P V, 2010-08-02
Type http://www.w3.org/2002/07/owl#Class
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