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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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Id | http://purl.obolibrary.org/obo/HINO_0008083
http://purl.obolibrary.org/obo/HINO_0008083
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Preferred Name | NLRC5 interacts with RIG-I/MDA5 and inhibit IPS-1 binding |
Definitions |
Reviewed: Kawai, T, Akira, S, 2010-10-30
Edited: Garapati, P V, 2010-08-02
NLRC5 competes with IPS-1 for binding to the CARD domain of RIG-I/MDA5. NLRC5 specifically recognize the CARD domains of RIG-I/MDA5 when the CARD domains become accessible after viral infection, leading to dampened activation of IRF3.
Authored: Garapati, P V, 2010-08-02
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
label |
NLRC5 interacts with RIG-I/MDA5 and inhibit IPS-1 binding
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comment |
Reviewed: Kawai, T, Akira, S, 2010-10-30
Edited: Garapati, P V, 2010-08-02
NLRC5 competes with IPS-1 for binding to the CARD domain of RIG-I/MDA5. NLRC5 specifically recognize the CARD domains of RIG-I/MDA5 when the CARD domains become accessible after viral infection, leading to dampened activation of IRF3.
Authored: Garapati, P V, 2010-08-02
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prefLabel |
NLRC5 interacts with RIG-I/MDA5 and inhibit IPS-1 binding
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definition source |
Pubmed20434986
Reactome, http://www.reactome.org
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prefixIRI |
HINO:0008083
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seeAlso |
Reactome Database ID Release 43937343
ReactomeREACT_25113
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subClassOf | |
type | |
has input | |
has output |
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