Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Beta defensin 103 activates TLR1:TLR2
Synonyms
Definitions

Beta defensin 103 (hBD-3) can induce expression of the costimulatory molecules CD80, CD86 and CD40 on monocytes and myeloid dendritic cells in a Toll-like receptor (TLR)-dependent manner. Activation by hBD-3 is mediated by an interaction that requires TLRs 1 and 2 (Funderburg et al. 2007, 2011). Reviewed: McDermott, AM, 2011-11-03 Edited: Jupe, S, 2011-11-07 Authored: Jupe, S, 2011-11-07

ID

http://purl.obolibrary.org/obo/HINO_0008036

comment

Beta defensin 103 (hBD-3) can induce expression of the costimulatory molecules CD80, CD86 and CD40 on monocytes and myeloid dendritic cells in a Toll-like receptor (TLR)-dependent manner. Activation by hBD-3 is mediated by an interaction that requires TLRs 1 and 2 (Funderburg et al. 2007, 2011).

Reviewed: McDermott, AM, 2011-11-03

Edited: Jupe, S, 2011-11-07

Authored: Jupe, S, 2011-11-07

definition source

Pubmed21896010

Reactome, http://www.reactome.org

Pubmed18006661

has input

http://purl.obolibrary.org/obo/HINO_0005990

http://purl.obolibrary.org/obo/UniProt_P81534

has output

http://purl.obolibrary.org/obo/HINO_0003202

label

Beta defensin 103 activates TLR1:TLR2

prefixIRI

HINO:0008036

prefLabel

Beta defensin 103 activates TLR1:TLR2

seeAlso

ReactomeREACT_115718

Reactome Database ID Release 431974676

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
There are currently no mappings for this class.