loading...| Preferred Name | Beta-defensins are secreted | |
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Authored: Jupe, S, 2011-04-28 Reviewed: McDermott, AM, 2011-11-03 Edited: Jupe, S, 2011-07-27 Beta defensin precursors are more simple in structure than those of alpha defensins, having a signal sequence, a short or absent propiece and the mature defensin sequence at the C-terminus. The signal sequence is cleaved off by a signal peptidase in the endoplasmic reticulum (Ganz 2003). Mature beta defensins 1, 2, 3, and 4 are secreted primarily by epithelial cells but are also produced by some immune cells such as monocytes, macrophages and dendritic cells (Duits et al. 2000, Ryan et al. 2003). |
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http://purl.obolibrary.org/obo/HINO_0008032 |
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Authored: Jupe, S, 2011-04-28 Reviewed: McDermott, AM, 2011-11-03 Edited: Jupe, S, 2011-07-27 Beta defensin precursors are more simple in structure than those of alpha defensins, having a signal sequence, a short or absent propiece and the mature defensin sequence at the C-terminus. The signal sequence is cleaved off by a signal peptidase in the endoplasmic reticulum (Ganz 2003). Mature beta defensins 1, 2, 3, and 4 are secreted primarily by epithelial cells but are also produced by some immune cells such as monocytes, macrophages and dendritic cells (Duits et al. 2000, Ryan et al. 2003). |
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| definition source |
Pubmed2997278 Reactome, http://www.reactome.org Pubmed9541493 Pubmed15019211 Pubmed12153515 Pubmed21122132 |
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Beta-defensins are secreted |
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HINO:0008032 |
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Beta-defensins are secreted |
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ReactomeREACT_116066 Reactome Database ID Release 431471322 |
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