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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Dimerization of Phospho IRF3 or phospho IRF7 | |
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| Definitions |
Reviewed: Kawai, T, Akira, S, 2010-10-30 Phosphorylation of these transcription factors IRF3 and IRF7 results in a conformational change that allows their dimerization to form homo- or hetero dimers. Each of the three different combinations of dimers (IRF3:IRF3, IRF7:IRF7 and IRF3:IRF7) may selectively effect the transcription of IFN-alpha gene subfamilies and IFN-beta genes. Edited: Garapati, P V, 2010-08-02 has a Stoichiometric coefficient of 3 Authored: Garapati, P V, 2010-08-02 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0007960 |
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| comment |
Reviewed: Kawai, T, Akira, S, 2010-10-30 Phosphorylation of these transcription factors IRF3 and IRF7 results in a conformational change that allows their dimerization to form homo- or hetero dimers. Each of the three different combinations of dimers (IRF3:IRF3, IRF7:IRF7 and IRF3:IRF7) may selectively effect the transcription of IFN-alpha gene subfamilies and IFN-beta genes. Edited: Garapati, P V, 2010-08-02 has a Stoichiometric coefficient of 3 Authored: Garapati, P V, 2010-08-02
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| definition source |
Reactome, http://www.reactome.org Pubmed12604599
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| has output |
http://purl.obolibrary.org/obo/HINO_0005744 |
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| label |
Dimerization of Phospho IRF3 or phospho IRF7
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| prefixIRI |
HINO:0007960
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| prefLabel |
Dimerization of Phospho IRF3 or phospho IRF7
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| seeAlso |
ReactomeREACT_24983 Reactome Database ID Release 431028821
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