Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Processing of caspases
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Reviewed: Kawai, T, Akira, S, 2010-10-30 Edited: Garapati, P V, 2010-08-02 Authored: Garapati, P V, 2010-08-02 Processing of caspases is required for activation of downstream signaling and dsRNA stimulation inducese the processing of these caspases. The nonapoptotic caspase function of both caspase-8 and -10 does not require the protease activity and the DED-containing prodomains are sufficient for NF-kB activation.

ID

http://purl.obolibrary.org/obo/HINO_0007941

comment

has a Stoichiometric coefficient of 2

Reviewed: Kawai, T, Akira, S, 2010-10-30

Edited: Garapati, P V, 2010-08-02

Authored: Garapati, P V, 2010-08-02

Processing of caspases is required for activation of downstream signaling and dsRNA stimulation inducese the processing of these caspases. The nonapoptotic caspase function of both caspase-8 and -10 does not require the protease activity and the DED-containing prodomains are sufficient for NF-kB activation.

definition source

Pubmed12884866

Reactome, http://www.reactome.org

Pubmed18761323

Pubmed16585540

Pubmed11717445

Pubmed16618810

has input

http://purl.obolibrary.org/obo/HINO_0003434

has output

http://purl.obolibrary.org/obo/HINO_0003441

http://purl.obolibrary.org/obo/UniProt_Q92851

http://purl.obolibrary.org/obo/UniProt_Q14790

label

Processing of caspases

prefixIRI

HINO:0007941

prefLabel

Processing of caspases

seeAlso

Reactome Database ID Release 43933532

EC Number: 3.4.22

ReactomeREACT_24999

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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