loading...| Preferred Name | Recruitment of TRAF6/TRAF2 to IPS-1 | |
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| Definitions |
Reviewed: Kawai, T, Akira, S, 2010-10-30 IPS-1 interacts with TRAF2 and TRAF6 through its consensus TRAF-interaction motif (TIM) (TRAF2 143-PVGET-147 and TRAF6 153-PGENSE-158 & 455-PEENEY-460). Although IPS-1 can bind to both TRAF6 and TRAF2, TRAF2 binding is not required for IPS-1 activation of NF-kB. Edited: Garapati, P V, 2010-08-02 Authored: Garapati, P V, 2010-08-02 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0007932 |
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| comment |
Reviewed: Kawai, T, Akira, S, 2010-10-30 IPS-1 interacts with TRAF2 and TRAF6 through its consensus TRAF-interaction motif (TIM) (TRAF2 143-PVGET-147 and TRAF6 153-PGENSE-158 & 455-PEENEY-460). Although IPS-1 can bind to both TRAF6 and TRAF2, TRAF2 binding is not required for IPS-1 activation of NF-kB. Edited: Garapati, P V, 2010-08-02 Authored: Garapati, P V, 2010-08-02 |
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| definition source |
Pubmed19479062 Pubmed16153868 Pubmed17029998 Reactome, http://www.reactome.org |
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| label |
Recruitment of TRAF6/TRAF2 to IPS-1 |
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| prefixIRI |
HINO:0007932 |
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| prefLabel |
Recruitment of TRAF6/TRAF2 to IPS-1 |
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| seeAlso |
Reactome Database ID Release 43918230 ReactomeREACT_25262 |
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