loading...| Preferred Name | Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 | |
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| Definitions |
Reviewed: Kawai, T, Akira, S, 2010-10-30 TANK acts as an adapter protein and regulates the assembly of TBK1/IKK epsilon complex with upstream signaling molecules. SIKE (for Suppressor of IKKepsilon) interacts with IKKepsilon and TBK1. SIKE is associated with TBK1 under physiological condition and dissociated from TBK1 upon viral infection. Overexpression of SIKE disrupted the interactions of IKKepsilon or TBK1 with RIG-1. Edited: Garapati, P V, 2010-08-02 Authored: Garapati, P V, 2010-08-02 |
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http://purl.obolibrary.org/obo/HINO_0007928 |
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| comment |
Reviewed: Kawai, T, Akira, S, 2010-10-30 TANK acts as an adapter protein and regulates the assembly of TBK1/IKK epsilon complex with upstream signaling molecules. SIKE (for Suppressor of IKKepsilon) interacts with IKKepsilon and TBK1. SIKE is associated with TBK1 under physiological condition and dissociated from TBK1 upon viral infection. Overexpression of SIKE disrupted the interactions of IKKepsilon or TBK1 with RIG-1. Edited: Garapati, P V, 2010-08-02 Authored: Garapati, P V, 2010-08-02 |
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| definition source |
Pubmed19479062 Pubmed12133833 Reactome, http://www.reactome.org Pubmed10581243 |
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Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 |
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| prefixIRI |
HINO:0007928 |
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Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 |
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ReactomeREACT_25079 Reactome Database ID Release 43933527 |
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