loading...| Preferred Name | CYLD mediated deubiquitination of RIG-I | |
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| Definitions |
Reviewed: Kawai, T, Akira, S, 2010-10-30 CYLD is an ovarian tumor (OTU) domain-containing deubiquitinating enzyme (DUB) and has been identified as a negative regulator of RIG-I mediated antiviral signaling. CYLD associates with the CARD domain of RIG-I and removes K63-linked ubiquitin from the RIG-I CARDs that are conjugated by the E3 ubiquitin ligase, TRIM25 and RNF135. Authored: Garapati, P V, 2010-08-02 Edited: Garapati, P V, 2010-08-22 |
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http://purl.obolibrary.org/obo/HINO_0007910 |
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| comment |
Reviewed: Kawai, T, Akira, S, 2010-10-30 CYLD is an ovarian tumor (OTU) domain-containing deubiquitinating enzyme (DUB) and has been identified as a negative regulator of RIG-I mediated antiviral signaling. CYLD associates with the CARD domain of RIG-I and removes K63-linked ubiquitin from the RIG-I CARDs that are conjugated by the E3 ubiquitin ligase, TRIM25 and RNF135. Authored: Garapati, P V, 2010-08-02 Edited: Garapati, P V, 2010-08-22 |
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Pubmed18467330 Pubmed18636086 Reactome, http://www.reactome.org |
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CYLD mediated deubiquitination of RIG-I |
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HINO:0007910 |
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CYLD mediated deubiquitination of RIG-I |
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Reactome Database ID Release 43936390 ReactomeREACT_25235 |
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