loading...| Preferred Name | CBL ubiquitinates PI3K | |
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| Definitions |
Authored: Ray, KP, 2010-05-17 Cbl is an E3 ubiquitin-protein ligase that negatively regulates signaling pathways by targeting proteins for ubiquitination and proteasomal degradation (Rao et al. 2002). Cbl-B targets PI3K for ubiquitination and degradation in T cells (Fang et al. 2000). Similarly, Cbl activation by tyrosine phosphorylation increases PI3K ubiquitination and proteasomal degradation (Dufour et al. 2008). Edited: Jupe, S, 2010-08-06 Reviewed: Lopez, AF, 2010-09-06 Reviewed: Hercus, TR, 2010-09-06 |
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http://purl.obolibrary.org/obo/HINO_0007495 |
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Authored: Ray, KP, 2010-05-17 Cbl is an E3 ubiquitin-protein ligase that negatively regulates signaling pathways by targeting proteins for ubiquitination and proteasomal degradation (Rao et al. 2002). Cbl-B targets PI3K for ubiquitination and degradation in T cells (Fang et al. 2000). Similarly, Cbl activation by tyrosine phosphorylation increases PI3K ubiquitination and proteasomal degradation (Dufour et al. 2008). Edited: Jupe, S, 2010-08-06 Reviewed: Lopez, AF, 2010-09-06 Reviewed: Hercus, TR, 2010-09-06 |
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Reactome, http://www.reactome.org Pubmed18374639 Pubmed11087752 Pubmed11994499 |
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CBL ubiquitinates PI3K |
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HINO:0007495 |
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CBL ubiquitinates PI3K |
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Reactome Database ID Release 43912627 ReactomeREACT_23869 |
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