Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Syk binds IL2RB
Synonyms
Definitions

Reviewed: Dooms, H, 2011-03-17 Reviewed: Villarino, A, 2011-02-11 Authored: Ray, KP, 2010-05-17 Syk binds to the serine-rich (aa 267 to 322) S region of IL2RB and becomes activated upon IL-2 stimulation (Minami et al. 1995).<br>Syk is shown here binding with the IL2:IL2RB trimer:p-JAK1:JAK3 complex but it may become associated at an earlier stage of receptor activation. Edited: Jupe, S, 2010-08-06

ID

http://purl.obolibrary.org/obo/HINO_0007421

comment

Reviewed: Dooms, H, 2011-03-17

Reviewed: Villarino, A, 2011-02-11

Authored: Ray, KP, 2010-05-17

Syk binds to the serine-rich (aa 267 to 322) S region of IL2RB and becomes activated upon IL-2 stimulation (Minami et al. 1995).<br>Syk is shown here binding with the IL2:IL2RB trimer:p-JAK1:JAK3 complex but it may become associated at an earlier stage of receptor activation.

Edited: Jupe, S, 2010-08-06

definition source

Pubmed7600304

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/UniProt_P43405

http://purl.obolibrary.org/obo/HINO_0027369

has output

http://purl.obolibrary.org/obo/HINO_0026338

label

Syk binds IL2RB

prefixIRI

HINO:0007421

prefLabel

Syk binds IL2RB

seeAlso

ReactomeREACT_27313

Reactome Database ID Release 43508292

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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