Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

IRAK1 induces oligomerisation of TRAF6
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 TRAF6 oligomerization is induced by IRAK1. The TRAF6 oligomer consists of more than two molecules of TRAF6; thermodynamic data for TRAF2 strongly suggests that it is functionally a trimer (Rawlings et al. 2006). TRAF6 is represented here as a trimer, though the extent and significance of TRAF6 oligomerization is unclear. Oligomerisation may be assisted by TIFA (TRAF-interacting protein with a FHA domain; Takatsuna et al. 2003). Edited: Jupe, S, 2010-05-17

ID

http://purl.obolibrary.org/obo/HINO_0007286

comment

has a Stoichiometric coefficient of 2

Authored: Ray, KP, 2010-05-17

Reviewed: Pinteaux, E, 2010-05-17

TRAF6 oligomerization is induced by IRAK1. The TRAF6 oligomer consists of more than two molecules of TRAF6; thermodynamic data for TRAF2 strongly suggests that it is functionally a trimer (Rawlings et al. 2006). TRAF6 is represented here as a trimer, though the extent and significance of TRAF6 oligomerization is unclear. Oligomerisation may be assisted by TIFA (TRAF-interacting protein with a FHA domain; Takatsuna et al. 2003).

Edited: Jupe, S, 2010-05-17

definition source

Pubmed12566447

Pubmed18070982

Pubmed17063183

Pubmed10908665

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/UniProt_Q9Y4K3

http://purl.obolibrary.org/obo/HINO_0027442

has output

http://purl.obolibrary.org/obo/HINO_0027440

label

IRAK1 induces oligomerisation of TRAF6

prefixIRI

HINO:0007286

prefLabel

IRAK1 induces oligomerisation of TRAF6

seeAlso

ReactomeREACT_22416

Reactome Database ID Release 43450173

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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