loading...| Preferred Name | The IKKB complex phosphorylates NFkB p105 | |
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has a Stoichiometric coefficient of 2 Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 NFkappaB p105 protein (p105) is a precursor of the NFkappaB p50 subunit and an inhibitor of NFkappaB. The IkappaB kinase (IKK) complex phosphorylates p105 on S927 within the PEST region. TNF-alpha-induced p105 proteolysis additionally requires the phosphorylation of S932. Purified IKK (IKK1) or IKKB (IKK2) can phosphorylate both these regulatory serines in vitro. Edited: Jupe, S, 2010-05-17 |
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http://purl.obolibrary.org/obo/HINO_0007281 |
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has a Stoichiometric coefficient of 2 Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 NFkappaB p105 protein (p105) is a precursor of the NFkappaB p50 subunit and an inhibitor of NFkappaB. The IkappaB kinase (IKK) complex phosphorylates p105 on S927 within the PEST region. TNF-alpha-induced p105 proteolysis additionally requires the phosphorylation of S932. Purified IKK (IKK1) or IKKB (IKK2) can phosphorylate both these regulatory serines in vitro. Edited: Jupe, S, 2010-05-17 |
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Reactome, http://www.reactome.org Pubmed12482991 |
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The IKKB complex phosphorylates NFkB p105 |
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HINO:0007281 |
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The IKKB complex phosphorylates NFkB p105 |
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ReactomeREACT_22418 EC Number: 2.7.11.10 Reactome Database ID Release 43451603 |
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