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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | IL1 receptor antagonist protein binds Interleukin 1 receptors | |
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| Definitions |
Authored: Ray, KP, 2010-05-17 The interleukin 1 receptor antagonist protein (ILRAP or IL1RN) is a member of the IL1 family that binds to IL1R1 (and with much lower affinity IL1R2) but does not elicit a signaling response. By competing with IL1 for IL1R1 binding ILRAP acts as a natural antagonist, inhibiting the biological actions of both agonist forms of IL1 (IL1 alpha and IL1 beta). Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-17 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0007221 |
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| comment |
Authored: Ray, KP, 2010-05-17 The interleukin 1 receptor antagonist protein (ILRAP or IL1RN) is a member of the IL1 family that binds to IL1R1 (and with much lower affinity IL1R2) but does not elicit a signaling response. By competing with IL1 for IL1R1 binding ILRAP acts as a natural antagonist, inhibiting the biological actions of both agonist forms of IL1 (IL1 alpha and IL1 beta). Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-17
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| definition source |
Pubmed1828071 Reactome, http://www.reactome.org Pubmed2139180
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| label |
IL1 receptor antagonist protein binds Interleukin 1 receptors
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| prefixIRI |
HINO:0007221
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| prefLabel |
IL1 receptor antagonist protein binds Interleukin 1 receptors
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| seeAlso |
ReactomeREACT_22331 Reactome Database ID Release 43445757
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