loading...| Preferred Name | IL1R1:IL1:IL1RAP binds MYD88 homodimer | |
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| Definitions |
MYD88 is a cytoplasmic adaptor protein that is recruited to the intracellular region of the IL1 receptor complex following IL1 stimulation. MYD88 binds to the complex of the two receptor chains and subsequently to IL-1 receptor-associated kinase 4 (IRAK4). This complex is the minimum required for signaling (Brikos et al. 2007). Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-17 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0007206 |
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| comment |
MYD88 is a cytoplasmic adaptor protein that is recruited to the intracellular region of the IL1 receptor complex following IL1 stimulation. MYD88 binds to the complex of the two receptor chains and subsequently to IL-1 receptor-associated kinase 4 (IRAK4). This complex is the minimum required for signaling (Brikos et al. 2007). Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-17 |
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| definition source |
Reactome, http://www.reactome.org Pubmed9430229 Pubmed17507369 |
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IL1R1:IL1:IL1RAP binds MYD88 homodimer |
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| prefixIRI |
HINO:0007206 |
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IL1R1:IL1:IL1RAP binds MYD88 homodimer |
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| seeAlso |
ReactomeREACT_22154 Reactome Database ID Release 43450133 |
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