loading...| Preferred Name | IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 | |
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| Definitions |
MYD88 is a cytoplasmic adaptor protein that is recruited to the intracellular region of the IL1 receptor complex following IL1 stimulation. MYD88 binds to the complex of the two receptor chains and subsequently to IL-1 receptor-associated kinase 4 (IRAK4). This complex is the minimum required for signaling (Brikos et al. 2007). Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-17 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0007199 |
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| comment |
MYD88 is a cytoplasmic adaptor protein that is recruited to the intracellular region of the IL1 receptor complex following IL1 stimulation. MYD88 binds to the complex of the two receptor chains and subsequently to IL-1 receptor-associated kinase 4 (IRAK4). This complex is the minimum required for signaling (Brikos et al. 2007). Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-17 |
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| definition source |
Reactome, http://www.reactome.org Pubmed12538665 Pubmed17507369 |
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| label |
IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 |
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| prefixIRI |
HINO:0007199 |
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| prefLabel |
IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 |
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| seeAlso |
ReactomeREACT_22326 Reactome Database ID Release 43446648 |
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