Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

The Interleukin 1 receptor complex binds Tollip
Synonyms
Definitions

Toll-interacting protein (TOLLIP) binds to IRAK1 and IL-1RAP within the receptor complex. TOLLIP has the capacity to act as an ubiquitin-binding receptor for ubiquitinated IL1R1, linking IL1R to endosomal degradation. Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-17

ID

http://purl.obolibrary.org/obo/HINO_0007197

comment

Toll-interacting protein (TOLLIP) binds to IRAK1 and IL-1RAP within the receptor complex. TOLLIP has the capacity to act as an ubiquitin-binding receptor for ubiquitinated IL1R1, linking IL1R to endosomal degradation.

Authored: Ray, KP, 2010-05-17

Reviewed: Pinteaux, E, 2010-05-17

Edited: Jupe, S, 2010-05-17

definition source

Pubmed10854325

Reactome, http://www.reactome.org

Pubmed17113392

has input

http://purl.obolibrary.org/obo/UniProt_Q9H0E2

http://purl.obolibrary.org/obo/HINO_0027461

has output

http://purl.obolibrary.org/obo/HINO_0027466

label

The Interleukin 1 receptor complex binds Tollip

prefixIRI

HINO:0007197

prefLabel

The Interleukin 1 receptor complex binds Tollip

seeAlso

Reactome Database ID Release 43446868

ReactomeREACT_22120

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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