Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Activation of ISG15 by UBE1L E1 ligase
Synonyms
Definitions

Ubiquitin ligase UBE1L is the ISG15 activating enzyme. UBE1L activates ISG15 in an ATP-dependent process that links UBE1L to ISG15 via a thioester bond. Arginine 153 (R153) in human ISG15 is identified as the key residue for ISG15 and UBE1L's interaction. Authored: Garapati, P V, 2011-01-18 Reviewed: Zhang, DE, 2011--0-2- Edited: Garapati, P V, 2011-01-18

ID

http://purl.obolibrary.org/obo/HINO_0007161

comment

Ubiquitin ligase UBE1L is the ISG15 activating enzyme. UBE1L activates ISG15 in an ATP-dependent process that links UBE1L to ISG15 via a thioester bond. Arginine 153 (R153) in human ISG15 is identified as the key residue for ISG15 and UBE1L's interaction.

Authored: Garapati, P V, 2011-01-18

Reviewed: Zhang, DE, 2011--0-2-

Edited: Garapati, P V, 2011-01-18

definition source

Pubmed19073728

Reactome, http://www.reactome.org

Pubmed18583345

has input

http://purl.obolibrary.org/obo/UniProt_P41226

http://purl.obolibrary.org/obo/UniProt_P05161

http://purl.obolibrary.org/obo/CHEBI_15422

has output

http://purl.obolibrary.org/obo/HINO_0027418

http://purl.obolibrary.org/obo/CHEBI_29888

http://purl.obolibrary.org/obo/CHEBI_16027

label

Activation of ISG15 by UBE1L E1 ligase

prefixIRI

HINO:0007161

prefLabel

Activation of ISG15 by UBE1L E1 ligase

seeAlso

ReactomeREACT_116132

EC Number: 6.3.2.19

Reactome Database ID Release 431169397

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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