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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Interaction of E3 ligase with ISG15:E2 complex | |
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| Definitions |
Ubiquitin ligase HERC5/CEB1 appears to be the predominant E3 ligase for ISGylation; EFP and HHARI/ARIH1 have also been reported as ISG15 E3 ligases. The E3 ligase recognizes specific target substrates and mediates the transfer of ISG15 from E2 to the substrate. Authored: Garapati, P V, 2011-01-18 Reviewed: Zhang, DE, 2011--0-2- Edited: Garapati, P V, 2011-01-18 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0007159 |
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| comment |
Ubiquitin ligase HERC5/CEB1 appears to be the predominant E3 ligase for ISGylation; EFP and HHARI/ARIH1 have also been reported as ISG15 E3 ligases. The E3 ligase recognizes specific target substrates and mediates the transfer of ISG15 from E2 to the substrate. Authored: Garapati, P V, 2011-01-18 Reviewed: Zhang, DE, 2011--0-2- Edited: Garapati, P V, 2011-01-18
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| definition source |
Pubmed17289916 Reactome, http://www.reactome.org Pubmed16407192 Pubmed16815975 Pubmed16352599
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| label |
Interaction of E3 ligase with ISG15:E2 complex
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| prefixIRI |
HINO:0007159
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| prefLabel |
Interaction of E3 ligase with ISG15:E2 complex
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| seeAlso |
Reactome Database ID Release 431169403 ReactomeREACT_116157
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