loading...| Preferred Name | Transphosphorylation of JAK1 | |
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| Definitions |
has a Stoichiometric coefficient of 2 Authored: Garapati, P V, 2010-06-08 Reviewed: Abdul-Sater, AA, Schindler, C, 2010-08-17 The initial phosphorylation of JAK1 and JAK2 is mediated by JAK2. Autophosphorylated JAK2 may transphopshorylate JAK1 bound to IFNGR1 chain. Tyrosine 1033 in the activation loop of the JAK1 kinase domain may be the target for transphosphorylation (phosphorylation site mentioned here is based on sequence similarity with all the other JAK kinases). Edited: Garapati, P V, 2010-07-07 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0007114 |
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| comment |
has a Stoichiometric coefficient of 2 Authored: Garapati, P V, 2010-06-08 Reviewed: Abdul-Sater, AA, Schindler, C, 2010-08-17 The initial phosphorylation of JAK1 and JAK2 is mediated by JAK2. Autophosphorylated JAK2 may transphopshorylate JAK1 bound to IFNGR1 chain. Tyrosine 1033 in the activation loop of the JAK1 kinase domain may be the target for transphosphorylation (phosphorylation site mentioned here is based on sequence similarity with all the other JAK kinases). Edited: Garapati, P V, 2010-07-07 |
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| definition source |
Pubmed14525967 Reactome, http://www.reactome.org Pubmed8631301 |
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| label |
Transphosphorylation of JAK1 |
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| prefixIRI |
HINO:0007114 |
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| prefLabel |
Transphosphorylation of JAK1 |
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| seeAlso |
ReactomeREACT_24928 EC Number: 2.7.10 Reactome Database ID Release 43873918 |
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