loading...| Preferred Name | IL6:IL6RA binds JAKs:IL6RB (gp130) | |
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| Definitions |
Authored: Ray, K, 2010-12-13 Edited: Jupe, S, 2010-12-10 The complex of IL-6 bound to the IL-6 receptor alpha subunit binds the IL-6 receptor beta subunit gp130. Site II of IL-6 within the binary complex interacts with the cytokine binding-homology region of gp130. Subsequently, site III of IL-6 interacts with the gp130 immunoglobulin-like activation domain. Reviewed: Rose-John, S, 2011-02-11 |
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http://purl.obolibrary.org/obo/HINO_0006460 |
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| comment |
Authored: Ray, K, 2010-12-13 Edited: Jupe, S, 2010-12-10 The complex of IL-6 bound to the IL-6 receptor alpha subunit binds the IL-6 receptor beta subunit gp130. Site II of IL-6 within the binary complex interacts with the cytokine binding-homology region of gp130. Subsequently, site III of IL-6 interacts with the gp130 immunoglobulin-like activation domain. Reviewed: Rose-John, S, 2011-02-11 |
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| definition source |
Reactome, http://www.reactome.org Pubmed2788034 |
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IL6:IL6RA binds JAKs:IL6RB (gp130) |
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HINO:0006460 |
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IL6:IL6RA binds JAKs:IL6RB (gp130) |
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ReactomeREACT_27227 Reactome Database ID Release 431067688 |
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