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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0006398
http://purl.obolibrary.org/obo/HINO_0006398
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|---|---|
| Preferred Name | Growth hormone forms dimers and oligomers |
| Definitions |
Authored: Jupe, S, 2010-10-14
Reviewed: Waters, MJ, 2011-06-23
Human growth hormone (GH) is a heterogeneous protein hormone consisting of several isoforms. The peptide is encoded by 2 genes, GH1 and GH2, both give rise to multiple variant forms. Post-translational modification including oligomerization increases the variation (Baumann 2009). Approximately 14% of circulating human Growth Hormone (GH) is in dimer or oligomer form, this number varying from 0 to 100% (Kublickas et al. 2006). The biological activity of these oligomeric forms is variably diminished when compared to the monomer (Baumann 2009).
Edited: Jupe, S, 2011-06-10
Reviewed: Herington, AC, 2011-06-13
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Growth hormone forms dimers and oligomers
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| comment |
Authored: Jupe, S, 2010-10-14
Reviewed: Waters, MJ, 2011-06-23
Human growth hormone (GH) is a heterogeneous protein hormone consisting of several isoforms. The peptide is encoded by 2 genes, GH1 and GH2, both give rise to multiple variant forms. Post-translational modification including oligomerization increases the variation (Baumann 2009). Approximately 14% of circulating human Growth Hormone (GH) is in dimer or oligomer form, this number varying from 0 to 100% (Kublickas et al. 2006). The biological activity of these oligomeric forms is variably diminished when compared to the monomer (Baumann 2009).
Edited: Jupe, S, 2011-06-10
Reviewed: Herington, AC, 2011-06-13
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| prefLabel |
Growth hormone forms dimers and oligomers
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| definition source |
Pubmed19467614
Reactome, http://www.reactome.org
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| prefixIRI |
HINO:0006398
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| seeAlso |
ReactomeREACT_111071
Reactome Database ID Release 43982765
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| subClassOf | |
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| has input | |
| has output |
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