Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

GHBP binds GHR
Synonyms
Definitions

GHBP, the ectodomain of GHR cleaved from membrane-bound GHR can form a heterodimer with GHR. This is not capable of signaling and may be a negative regulatory influence. GHBP can also inhibit signaling by competing with the full length receptor for GH binding. Reviewed: Waters, MJ, 2011-06-23 Edited: Jupe, S, 2011-06-10 Authored: Herington, AC, 2011-06-13

ID

http://purl.obolibrary.org/obo/HINO_0006351

comment

GHBP, the ectodomain of GHR cleaved from membrane-bound GHR can form a heterodimer with GHR. This is not capable of signaling and may be a negative regulatory influence. GHBP can also inhibit signaling by competing with the full length receptor for GH binding.

Reviewed: Waters, MJ, 2011-06-23

Edited: Jupe, S, 2011-06-10

Authored: Herington, AC, 2011-06-13

definition source

Reactome, http://www.reactome.org

Pubmed9058373

has input

http://purl.obolibrary.org/obo/UniProt_P10912

has output

http://purl.obolibrary.org/obo/HINO_0026898

label

GHBP binds GHR

prefixIRI

HINO:0006351

prefLabel

GHBP binds GHR

seeAlso

ReactomeREACT_111073

Reactome Database ID Release 431362465

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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