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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | PTP1B binds the GH receptor complex | |
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| Definitions |
Authored: Jupe, S, 2010-10-14 PTP1B has been shown to associate with GH-dependent phosphorylated GHR and induce its dephosphorylation (Pasquali et al. 2003). It can also dephosphorylate JAK2 (Gu et al. 2003). Both have the effect of reducing JAK signaling. Reviewed: Waters, MJ, 2011-06-23 Edited: Jupe, S, 2011-06-10 Reviewed: Herington, AC, 2011-06-13 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0006340 |
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| comment |
Authored: Jupe, S, 2010-10-14 PTP1B has been shown to associate with GH-dependent phosphorylated GHR and induce its dephosphorylation (Pasquali et al. 2003). It can also dephosphorylate JAK2 (Gu et al. 2003). Both have the effect of reducing JAK signaling. Reviewed: Waters, MJ, 2011-06-23 Edited: Jupe, S, 2011-06-10 Reviewed: Herington, AC, 2011-06-13
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| definition source |
Pubmed12907755 Reactome, http://www.reactome.org Pubmed12748279
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| label |
PTP1B binds the GH receptor complex
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| prefixIRI |
HINO:0006340
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| prefLabel |
PTP1B binds the GH receptor complex
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| seeAlso |
Reactome Database ID Release 431168445 ReactomeREACT_111219
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