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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | STAT5 tyrosine phosphorylation | |
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| Definitions |
has a Stoichiometric coefficient of 2 Authored: Jupe, S, 2010-10-14 Reviewed: Waters, MJ, 2011-06-23 Stat5 tyrosine phosphorylation was seen in response to GH in CHO cells expressing mouse GHR forms capable of binding JAK2 (Smit et al. 1996). Similar results were obtained using the porcine receptor (Wang et al. 1996). Thus Jak2 phosphorylates Stat5, the phosphorylated monomers form dimers and translocate to the nucleus (Darnell et al. 1994). Edited: Jupe, S, 2011-06-10 Reviewed: Herington, AC, 2011-06-13 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0006323 |
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| comment |
has a Stoichiometric coefficient of 2 Authored: Jupe, S, 2010-10-14 Reviewed: Waters, MJ, 2011-06-23 Stat5 tyrosine phosphorylation was seen in response to GH in CHO cells expressing mouse GHR forms capable of binding JAK2 (Smit et al. 1996). Similar results were obtained using the porcine receptor (Wang et al. 1996). Thus Jak2 phosphorylates Stat5, the phosphorylated monomers form dimers and translocate to the nucleus (Darnell et al. 1994). Edited: Jupe, S, 2011-06-10 Reviewed: Herington, AC, 2011-06-13
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| definition source |
Pubmed8732683 Reactome, http://www.reactome.org Pubmed9121492 Pubmed8197455
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| label |
STAT5 tyrosine phosphorylation
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| prefixIRI |
HINO:0006323
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| prefLabel |
STAT5 tyrosine phosphorylation
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| seeAlso |
ReactomeREACT_111218 EC Number: 2.7.10 Reactome Database ID Release 431168394
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