Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

EGFR dimerization
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Reviewed: Muthuswamy, S, 2007-02-16 20:08:05 Authored: Castagnoli, L, 2006-10-10 13:09:34 EGF and other growth factors induce oligomerization of their specific receptors. Inactive EGFR monomers are in equilibrium with active EGFR dimers and binding of the EGF ligand stabilizes the active dimeric form.

ID

http://purl.obolibrary.org/obo/HINO_0004513

comment

has a Stoichiometric coefficient of 2

Reviewed: Muthuswamy, S, 2007-02-16 20:08:05

Authored: Castagnoli, L, 2006-10-10 13:09:34

EGF and other growth factors induce oligomerization of their specific receptors. Inactive EGFR monomers are in equilibrium with active EGFR dimers and binding of the EGF ligand stabilizes the active dimeric form.

definition source

Reactome, http://www.reactome.org

Pubmed8639530

has input

http://purl.obolibrary.org/obo/HINO_0011989

has output

http://purl.obolibrary.org/obo/HINO_0011991

label

EGFR dimerization

prefixIRI

HINO:0004513

prefLabel

EGFR dimerization

seeAlso

ReactomeREACT_9397

Reactome Database ID Release 43177922

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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