Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

EGFR binds EGF ligand
Synonyms
Definitions

Reviewed: Muthuswamy, S, 2007-02-16 20:08:05 Authored: Castagnoli, L, 2006-10-10 13:09:34 The prototypic receptor tyrosine kinase (RTK) EGFR is composed of 3 major domains; an extracellular domain linked via a single membrane-spanning domain to a cytoplasmic domain. EGF binds to the extracellular domain from where the signal is transmitted to the cytoplasmic domain.

ID

http://purl.obolibrary.org/obo/HINO_0004512

comment

Reviewed: Muthuswamy, S, 2007-02-16 20:08:05

Authored: Castagnoli, L, 2006-10-10 13:09:34

The prototypic receptor tyrosine kinase (RTK) EGFR is composed of 3 major domains; an extracellular domain linked via a single membrane-spanning domain to a cytoplasmic domain. EGF binds to the extracellular domain from where the signal is transmitted to the cytoplasmic domain.

definition source

Reactome, http://www.reactome.org

Pubmed8639530

has input

http://purl.obolibrary.org/obo/UniProt_P01133

http://purl.obolibrary.org/obo/UniProt_P00533

has output

http://purl.obolibrary.org/obo/HINO_0011989

label

EGFR binds EGF ligand

prefixIRI

HINO:0004512

prefLabel

EGFR binds EGF ligand

seeAlso

ReactomeREACT_9481

Reactome Database ID Release 43177942

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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