Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

DAG stimulates protein kinase C-delta
Synonyms
Definitions

Diacylglycerol (DAG) positively regulates the autophosphorylation of protein kinase C-delta (PKC-delta), which stimulates ERK1/2 and triggers neurite outgrowth. DAG also stimulates the translocation of PKC from the cytosol to the plasma membrane. PKC-delta contributes to growth factor specificity and response to neuronal cells by promoting cell-type-specific differences in growth factor signalling. DAG can also activate PKC-epsilon in the same manner. has a Stoichiometric coefficient of 3 Reviewed: Greene, LA, 2007-11-08 15:39:37

ID

http://purl.obolibrary.org/obo/HINO_0004493

comment

Diacylglycerol (DAG) positively regulates the autophosphorylation of protein kinase C-delta (PKC-delta), which stimulates ERK1/2 and triggers neurite outgrowth. DAG also stimulates the translocation of PKC from the cytosol to the plasma membrane. PKC-delta contributes to growth factor specificity and response to neuronal cells by promoting cell-type-specific differences in growth factor signalling. DAG can also activate PKC-epsilon in the same manner.

has a Stoichiometric coefficient of 3

Reviewed: Greene, LA, 2007-11-08 15:39:37

definition source

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/HINO_0025206

http://purl.obolibrary.org/obo/CHEBI_15422

has output

http://purl.obolibrary.org/obo/HINO_0025207

http://purl.obolibrary.org/obo/CHEBI_16761

label

DAG stimulates protein kinase C-delta

prefixIRI

HINO:0004493

prefLabel

DAG stimulates protein kinase C-delta

seeAlso

Reactome Database ID Release 43198314

ReactomeREACT_12062

EC Number: 2.7.11.13

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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