Preferred Name | Lambert-Eaton myasthenic syndrome | |
Synonyms |
Eaton-Lambert syndrome Lambert-Eaton syndrome LEMS |
|
Definitions |
A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. |
|
ID |
http://purl.obolibrary.org/obo/DOID_0050214 |
|
alternative label |
Eaton-Lambert syndrome Lambert-Eaton syndrome LEMS |
|
database_cross_reference |
UMLS_CUI:C0022972 ICD10CM:G70.80 ICD9CM:358.3 SNOMEDCT_US_2023_03_01:230688006 MESH:D015624 NCI:C3155 |
|
definition |
A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. |
|
has exact synonym |
Eaton-Lambert syndrome Lambert-Eaton syndrome LEMS |
|
has_obo_namespace |
disease_ontology |
|
id |
DOID:0050214 |
|
in_subset | ||
label |
Lambert-Eaton myasthenic syndrome |
|
notation |
DOID:0050214 |
|
note |
A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. |
|
preferred label |
Lambert-Eaton myasthenic syndrome |
|
prefLabel |
Lambert-Eaton myasthenic syndrome |
|
subClassOf |
http://purl.obolibrary.org/obo/DOID_439 |